Risk Factors
Exocrine pancreatic insufficiency is more likely to develop in individuals who engage in heavy alcohol consumption as it can result in inflammation of the pancreas. Additionally, individuals with immune system disorders are at an increased risk. People with cystic fibrosis, for instance, have a higher chance of developing this condition due to the production of thick mucus that can obstruct the pancreas. Other conditions such as Crohn’s disease, celiac disease, and Schwachman-Diamond syndrome also contribute to the likelihood of developing exocrine pancreatic insufficiency.
Signs of Exocrine Pancreatic Insufficiency
Exocrine pancreatic insufficiency (EPI) can initially be asymptomatic in mild cases. However, as the condition advances, various symptoms start to manifest. These commonly include abdominal discomfort or pain, along with a persistent feeling of excessive fullness. Additionally, individuals with EPI may experience bloating, excessive gas, and the passage of foul-smelling stools.
One notable effect of EPI is weight loss, which occurs due to the body’s inability to properly absorb fats and other essential nutrients.