Atheromas, also known as atherosclerotic plaques, refer to the buildup of various substances such as fat, cholesterol, calcium, connective tissue, and inflammatory cells within the walls of arteries. This gradual accumulation occurs over time and atheromas may not become apparent for months or even years. Over time, as the buildup increases, the artery walls narrow, leading to restricted blood flow or even complete blockage. Atheromas can have serious consequences, including the formation of blood clots, heart attacks, and strokes.
Understanding the Causes of Atheromas
Unraveling the precise origins of atheromas remains a challenge for scientists and medical professionals. However, they have identified that inflammation of the endothelium is a significant culprit. This inflammatory response is thought to be influenced by a combination of genetic predisposition and lifestyle choices. Ultimately, this inflammation sets off a chain reaction that attracts fat and cholesterol deposits, leading to the formation of atheromas. Several factors contribute to this process, including high blood pressure, diabetes, obesity, smoking, high cholesterol levels, age, and gender.
Understanding the Link between Rheumatoid Arthritis and Atheromas
Rheumatoid arthritis (RA) is a long-term inflammatory condition that primarily affects the joints, with a higher incidence in the hands and feet. Recent research has established a significant association between rheumatoid arthritis and the development of atheromas and atherosclerosis, two types of arterial plaque. In fact, scientific studies have identified two specific biomarkers present in individuals with RA, which play a crucial role in the formation of plaque within the arteries.