Understanding Jaundice
Jaundice, a common symptom of cholestasis, occurs when the normal flow of bile into the duodenum is hindered. This obstruction leads to a buildup of bilirubin, resulting in a yellow discoloration of the skin. In addition to the skin, the whites of the eyes may also become yellow. Furthermore, jaundice can cause itching of the skin, which is believed to be caused by an excess of bile accumulating in the skin.
Other Symptoms
Cholestasis can manifest in various ways, including several other symptoms. One common sign is the lightening of stool color due to the lack of bile. Additionally, fatty stools can occur because bile, which aids in digestion, is not flowing properly into the small intestine. Dark urine may also be observed as excess bilirubin is excreted by the kidneys.
If left untreated for an extended period, cholestasis can lead to malabsorption of calcium and vitamin D, resulting in bone loss. The specific symptoms experienced can vary depending on the underlying cause of cholestasis. Some individuals may experience vomiting, fever, abdominal pain, and loss of appetite. Another prevalent symptom is fatigue, which can be severe.