Treatment
When it comes to treating PANDAS, the approach varies depending on the type of infection. Typically, physicians will prescribe antibiotics as a first-line treatment. The American Academy of Pediatrics suggests that children with PANDAS should continue taking antibiotics for a minimum of five years after the last attack or until they reach 21 years of age.
In cases where antibiotics do not yield a positive response and severe symptoms persist, plasmapheresis may be recommended. This procedure involves removing harmful auto-antibodies from the blood to alleviate symptoms. Additionally, other treatment options such as steroids, behavioral therapies, and tonsillectomies may be considered to manage PANDAS effectively.
Prognosis
Early antibiotic treatment is considered crucial by PANDA specialists. While reactions to strep infections beyond the age of 12 are uncommon, there is speculation that PANDAS may cease after the onset of menses in females. However, it is possible for individuals to experience persistent low levels of OCD, tics, and anxiety for several months or even permanently. According to interviews with parents of children with the condition, approximately three percent continue to face issues into adulthood, although ongoing studies are being conducted to gain further insights. Researchers believe that over time, a child’s immune system will develop the appropriate antibody response to strep infections.