Hemodialysis and TLS
A connection has been found between reduced kidney function or estimated glomerular filtration and increased levels of phosphorus and uric acid. According to a study conducted in 1998, approximately 68% of 1200 individuals with non-Hodgkin’s lymphoma had pre-existing kidney dysfunction, which put them at a higher risk of experiencing severe medical complications. In order to regulate elevated levels of potassium, phosphate, and uric acid, doctors may recommend a procedure called hemodialysis. This treatment involves the removal of excess fluid and the cleansing of the blood when the kidneys are unable to effectively carry out these functions.
Dietary Recommendations for Managing TLS Risk
When it comes to patients at risk for tumor lysis syndrome (TLS), certain dietary considerations play a crucial role. Medical professionals often prescribe a low-potassium and low-phosphate diet to mitigate potential complications. Additionally, if phosphate levels are elevated, physicians may recommend phosphate binders, which, when taken during meals, hinder the absorption of phosphorus by the body. To address high uric acid levels, a low-purine diet is sometimes advised. Foods rich in purines, such as wild game, fish, organ meats, fatty foods, yeast, gravies, and liquor, are typically limited. However, the effectiveness of dietary interventions in regulating uric acid levels remains inadequately supported by documented evidence.