The Progestogen/Testosterone Shot
The Progestogen/Testosterone Shot is a method introduced in the 1970s, which involves the administration of an injection containing two hormones: progesterone and testosterone. The testosterone component of this injection is specifically designed to decrease male fertility, while progestogen enhances the effectiveness of testosterone. According to a trial conducted in 2016, these injections demonstrated a remarkable 98% efficacy in preventing pregnancy. However, it is important to note that 5% of the participants experienced a complete loss of fertility that was irreversible. Additionally, some individuals reported experiencing mood disorders and depression as side effects of the injections.
Gossypol: A Potentially Unsafe Male Contraceptive
Gossypol is a chemical compound naturally found in cotton seeds. In the past, scientists became intrigued by its potential as a male contraceptive after observing that men who consumed cottonseed experienced a decrease in fertility. However, further studies revealed alarming side effects associated with this compound.
One study discovered that approximately one-fifth of the male participants who took gossypol lost their ability to produce sperm, and unfortunately, this loss was irreversible. Additionally, gossypol was found to cause a reduction in potassium levels in the blood, leading to potential health issues such as fatigue, paralysis, arrhythmias, and even respiratory failure.
Considering these serious side effects, gossypol is no longer considered a safe option for use as a male contraceptive method. Further research is necessary to develop alternative, effective, and safer approaches in the field of male contraception.