Role of Reticulocytes in the Body
Reticulocytes play a crucial role in the body by maturing into fully functional red blood cells. These specialized cells are responsible for carrying oxygen to the different tissues and organs, while simultaneously removing carbon dioxide for exhalation through the lungs. The production rate of reticulocytes in the bone marrow is dynamic and adjusts in response to internal and external challenges to meet the body’s requirements.
Methods for Measuring Reticulocytes
When it comes to measuring reticulocytes, there are specific techniques employed in the blood lab. These techniques allow for accurate identification and counting of these unique cells.
One distinguishing feature of reticulocytes is the presence of mesh-like strands within their nucleus. To make these strands more visible and easily countable, they are stained with a blue pigment during laboratory analysis.
The process begins by obtaining a blood sample from the patient. This sample is then subjected to staining, typically using a supravital dye such as new methylene blue or brilliant cresyl blue. The dye helps in highlighting the reticulocytes, making them stand out from the other blood cells.
Once the staining is complete, a thin blood smear is prepared on a glass slide. This smear is examined under a microscope, usually at high magnification. By carefully scanning the slide, the lab technician can identify and count the reticulocytes present in the sample.
The final count is expressed as a percentage of reticulocytes out of one thousand red blood cells in the sample. This measurement provides valuable information about the bone marrow’s ability to produce new red blood cells, as well as the overall health of the patient’s blood.