Risk Factors for Granuloma Annulare
Granuloma annulare (GA) can be influenced by certain risk factors, including diabetes mellitus, autoimmune disorders, and thyroid disease. However, it is important to note that not everyone with these conditions will develop GA. Additionally, cancer can also act as a trigger for GA, particularly in older individuals. In cases where GA is associated with cancer, it tends to be more severe, and the skin lesions often do not respond well to treatment.
Prognosis
Granuloma annularae flare-ups that manifest as skin lesions typically resolve on their own within a few weeks. This implies that the lesions disappear without any medical intervention, although they may reoccur in many cases. For most individuals with localized GA, flare-ups cease within five years. The generalized form of the condition often heals spontaneously but may resurface after several months or even years. About 25% of non-localized GA cases persist for more than five years and, in some instances, can extend beyond ten years.