Possible Complications of Antiphospholipid Antibody Syndrome
Antiphospholipid antibody syndrome (APS) can give rise to severe complications that have the potential to be life-threatening. These complications include heart attacks, strokes, and kidney damage. In some cases, the formation of blood clots in deep veins of the leg, thigh, or pelvis can lead to a condition called deep vein thrombosis (DVT). DVT can cause symptoms such as shortness of breath and chest pain, and in severe cases, it can be fatal. Another common complication associated with APS is pulmonary embolism, which occurs when a blood clot travels to the lungs.
Pregnant women who have APS face an increased risk of stillbirths and miscarriages. However, with proper medical care, many women with the syndrome are able to have healthy and successful births.
Risk Factors
Antiphospholipid antibody syndrome (APS) primarily affects women, with a prevalence five times higher than in men. It commonly manifests between the ages of 30 and 40. Moreover, individuals with other autoimmune disorders have an increased likelihood of developing APS. Those afflicted with syphilis, hepatitis C, Lyme disease, or HIV/AIDS are also at a higher risk. Furthermore, certain blood pressure medications have been associated with the development of APS. Finally, it is worth noting that APS can have a familial predisposition.