Effects in Adulthood
As individuals with Fragile X Syndrome (FXS) transition into adulthood, they often experience various effects that are unique to this stage of life. In the case of boys with FXS, they tend to become more mild-mannered as they approach adulthood. Additionally, they develop a good sense of humor and demonstrate a remarkable level of diligence and determination when it comes to accomplishing tasks.
On the other hand, women with a full mutation and symptomatic FXS may exhibit a range of anxiety-related symptoms as they enter adulthood. These symptoms can include conditions such as obsessive-compulsive disorder, shyness, social avoidance, social anxiety, mood swings, and depression.
For men over the age of 50 with FXS, there is a possibility of experiencing certain physical symptoms. These symptoms may include tremors, a rapid onset of dementia, incontinence, as well as other symptoms commonly associated with movement disorders.
Autism in Fragile X Syndrome
Autism is a condition that is commonly observed in individuals with Fragile X Syndrome (FXS). However, the prevalence of autism in boys with FXS is higher compared to girls. This is primarily because autism usually develops in cases where there is a full X chromosome mutation, which is a rare occurrence in females.
In early childhood, children with FXS who have autism may display certain symptoms. These symptoms include stereotypies like biting, repetitive speech, hand-flapping, poor eye contact, and reduced or absent social interaction. Additionally, it is important to note that around 20 to 30 percent of children with FXS also experience developmental disorders that do not have a specific diagnosis.