Epithelial Barrier: Protection for Your Skin
The epithelial barrier is a crucial component of your skin’s defense system. It consists of a cornified envelope that envelops cornified cells, replacing their cell membrane. This envelope is formed by various types of keratin, which are proteins that connect with keratin filaments inside the cell as well as with the filaments of neighboring cells. Additionally, other proteins, known as desmosomes, interact with the keratin filaments to link epithelial cells together. Together, this intricate matrix of proteins creates a flexible and insoluble barrier that shields your skin from external threats.
Soft-Cornified Cells
On the human body, there are two types of cornified skin cells that provide a protective layer. Soft-cornified cells are found on the surface of mucous membranes and skin. As new cells grow, these cells naturally shed or desquamate. Meanwhile, the basal layer of the skin, located beneath the epidermis, contains keratinocytes responsible for producing keratin. These basal cells, also known as basal keratinocytes, play a crucial role in safeguarding the skin from various threats such as pathogens, heat, UV radiation, water loss, and environmental damage.