Complications Associated with Paget’s Disease
Paget’s disease can lead to various complications, with osteoarthritis being the most prevalent. This occurs when the shape of a bone is altered due to the disease, affecting the mechanics of the skeletal system. For instance, if Paget’s disease causes the femur bone to bow, it can result in an abnormal alignment of the leg, leading to increased stress on the knee joint and degeneration of its components. In addition to osteoarthritis, other complications that can arise from Paget’s disease include:
Non-Hereditary Cause of Paget’s Disease
Paget’s disease, a bone disorder, can also occur in individuals who do not have any genetic markers for the condition. In these cases, it is believed that the disease is triggered by a “slow virus” infection that remains dormant in the body for a prolonged period. This viral infection could be associated with various health issues such as measles, respiratory conditions, or meningitis. Slow virus infections typically have long incubation periods and do not exhibit any symptoms. However, if the individual experiences a health problem that weakens the immune system, the virus can become active again.