Genetics
Kallmann syndrome is typically not inherited through family history, but individuals with the condition can pass it on to their children through different genetic patterns. The specific gene involved determines the inheritance pattern, which can be autosomal-recessive when both parents are carriers, autosomal-dominant when one parent passes on the gene, or X-linked when the mother is the carrier. In cases of X-linked inheritance, mothers can pass the condition to their sons, while fathers cannot. Daughters have the potential to become carriers by inheriting the gene from either parent.
Symptoms of Kallmann Syndrome in Males
When it comes to Kallmann syndrome, males may exhibit certain symptoms, especially during infancy. These symptoms include having a small penis or undescended testes. However, most cases of Kallmann syndrome in males go undiagnosed until they reach puberty, where a lack of sexual development becomes apparent. One of the key indicators of Kallmann syndrome in males is the absence of facial and body hair growth, and they may also experience delayed growth spurts.