Side Effects of Lithium Orotate
When it comes to lithium, including the form known as lithium orotate, there is a concern about its narrow therapeutic index. This means that the difference between a dose that is effective and one that is toxic is quite small.
Experiencing toxicity from lithium can result in various side effects, such as vomiting, lethargy, and involuntary muscle movements. In more severe cases of long-term lithium toxicity, individuals may develop abnormalities with their heart and thyroid.
Research Supporting the Use of Lithium Orotate
There have been some studies conducted on the potential use of lithium orotate in the treatment of mood disorders. While the research is limited, most of the studies have been performed on rats to examine how the body absorbs, distributes, metabolizes, and excretes the drug.
When it comes to clinical studies involving humans, there is a scarcity of research available. However, one study did show promising results in using lithium orotate to aid patients recovering from substance disorders, specifically alcohol. The study found that lithium orotate helped reduce relapse rates among the participants. Out of the 42 individuals involved in the study, 23 remained sober for a duration of one to ten years after taking a daily dose of 150mg of lithium orotate for six months following their alcohol cessation.