Stages Four and Five
As Reye’s syndrome advances, it enters stage four, which is characterized by a more profound coma and dilated pupils that show minimal response to light. Additionally, liver dysfunction worsens during this stage, leading to the accumulation of fat in various organs. Subsequently, stage five rapidly follows stage four, bringing along seizures, multiple organ failure, and weakened or paralyzed limbs in addition to the existing coma. The final stage, stage five, culminates with hyperammonemia – an excess of ammonia in the bloodstream. At this point, toxins start to accumulate throughout the body due to the impaired functioning of both the liver and kidneys.
What Causes Reye’s Syndrome?
The exact cause of Reye’s syndrome remains unknown. However, there are several factors that have been associated with the development of this condition. Reye’s syndrome typically occurs shortly after a child has recovered from a viral illness like chickenpox or influenza, although it can also manifest three to five days after the initial onset. Studies suggest that around 90 percent of cases in children are linked to the use of medications containing salicylates. In addition, exposure to certain chemicals such as paint thinners and herbicides may also increase the risk of developing Reye’s syndrome.