The Impact of DES on Women’s Health
Prescription drugs can sometimes have unintended consequences, including the development of an incompetent cervix. During the period of 1938 to 1971, doctors prescribed a synthetic nonsteroidal estrogen known as diethylstilbestrol, or DES, to pregnant women to prevent complications related to pregnancy. However, it was later discovered that DES actually increased the risk of certain types of vaginal and cervical cancers, as well as breast cancer. Not only did the women who took DES face these risks, but their daughters also had an elevated chance of developing breast cancer. Additionally, these daughters were more likely to experience difficulties in conceiving, suffer from miscarriages, or have premature births due to abnormalities in the vagina and cervix.
Diagnosis
Identifying an incompetent cervix can only be done during pregnancy. However, it can be particularly difficult to diagnose during a woman’s first pregnancy, as doctors may not be aware of the condition. If a woman experiences symptoms of cervical insufficiency, a pelvic exam can be conducted to check if the amniotic sac is protruding through the cervical opening. Additionally, a transvaginal ultrasound can provide a clearer image. To further assess the situation, the doctor may order lab tests to check for any signs of inflammation or infection in the amniotic sac.